The use of any information provided on this web site is solely at your own risk. Continuous-dosing pack. Also, it is asked, How quickly does DIM work? Put the lubricant around the tampon and try to slide it out. Read More Which Type Of Supplement Will The Dietician Most Likely Recommend?Continue, Read More Where To Buy T-Drive Supplement?Continue, Read More What Is The Number One Food Supplement In The World?Continue, Read More What Is The Best Lactation Supplement?Continue, Read More What Does Pump Supplement Do?Continue, Read More Which Supplement Has Been Shown To Repair Connective Tissue?Continue, 2023 Health Articl - WordPress Theme by Kadence WP. Healthline Media does not provide medical advice, diagnosis, or treatment. How? While subjective, on. I stopped the DIM right after. Chan EK, Sepkovic DW, Bowne HJY, Yu GP, Schantz SP. Improving your diet. Perimenopause occurs between the ages of 40 and 50. There are many different opinions on when to take it, but the general consensus is that taking it every day for 3 weeks will be beneficial. Periods will start to become irregular, until they disappear altogether. Here's how it all goes down: You have 2 ovaries, and each one holds a bunch of eggs. No matter your medical history, its important to consult your healthcare provider before taking these supplements. This nutrient has a lot of potential hormonal health benefits for women particularly in the case of excess estrogen, which is why many people opt for the supplement. Keep in mind that human studies are needed. Fight zits and skin damage with all-natural, organic. Zeligs MA, Brownstone PK, Sharp ME, et al. tomatoes. A study showed that vitamin C was able to reduce heavy bleeding in 87% of women who participated. Should I keep taking it? When used at dosages of up to 150 mg daily for up to a year, it is probably safe for most individuals. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K, Helps prevent the effects of estrogen on cells, Lowers toxins produced by your bodys natural metabolism. Testosterone is an androgen that controls and governs masculine features such as male genital development, a deeper voice, and the distribution of body hair. However I also started to notice weight gain. All rights reserved. by: Wray. The best way to get any nutrient is through healthy eating. Changes in Hormone Levels. For the first few years after menstruation begins, long cycles are common. I didn't want to do either. While DIM can be derived from food, it would take eating a whole lot of broccoli to match what can be found in a supplement. Join in and write your own page! If you do decide to take Vitex, don't take it for longer than 3-6 months maximum at a time, then stop and see how your hormones are without it. You should only use natural remedies during your period if they . 3. Thanks Diane! For others, periods become significantly lighter. I know it removes excess estrogen but is there any chance it may remove too much? KEEPING IT REAL, WHILE KEEPING YOU EDUCATED. It helps keep my period-induced cystic acne at bay, reduces PMS symptoms and helps me be a generally happier person. So, which one is it: is estrogen supposed to be high or low during perimenopause? Headache, nausea, vomiting, gas, and diarrhea are the most prevalent adverse effects. Fibroids, polyps, and endometrial lesions, like those seen in endometriosis, can also be stimulated by estrogen. I'm also taking a b complex, iron and DIM supplements for estrogen issues. In place of supplements, include cruciferous vegetables in your diet. . In a randomized, placebo-controlled trial, women prescribed tamoxifen (a treatment for hormone-receptor positive breast cancer) were either assigned 150 mg of an oral DIM supplement or a placebo for a 12-month period. The week leading up to my period was so painful. As DIM supplements interact with estrogen levels, they may affect people with hormone-sensitive cancers or who are on hormone therapies. While this is not true for everyone, the root cause of PMS could be due to estrogen dominance. Less common side effects included nausea, diarrhea, vomiting and a skin rash. By helping the body maintain a more favorable estrogen profile, DIM may help mitigate the symptoms of perimenopause and menopause when the culprit is estrogen imbalance. Featuring a 28 day plan to take back your cycle and dozens of charts, checklists, and diagrams to help along the way. Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice thatis not captive to purely commercial interests, or blinded by academic and institutional hubris. In human research, doses typically range from 108900 mg per day though these studies were only related to treatments for cancer and prostate enlargement (8, 9, 14). Chasteberry and DIM are the greatest vitamins for hormone imbalance. Thats the bad news. Therefore, its best to talk to your healthcare provider to obtain personalized dosage recommendations based on your intended use. I also am looking for and hopeful to find a functional/holistic MD in my area but there aren't many and I'm doubtful that my insurance covers it. Heavy Menstrual Cycles Bloating. It also can inhibit the conversion of testosterone to estrogen, which may help balance these two hormones. Symptomatic Relief From Supplements Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. The best way to determine how much DIM you specifically need is to have lab testing that includes estrogen and estrogen metabolites. . Discuss any medication you are currently taking with your doctor before adding DIM to your regimen. Dim lights can also trigger migraine headaches for people who suffer from them. Since I made the change with dosage in late May (now September) I have had nearly perfect 24-26 day cycles and the . Low estrogen is typically seen in younger women and women approaching menopause. However, menstrual cycles tend to shorten and become more regular as you age. Would you prefer to share this page with others by linking to it? Estradiol and cognitive function: past, present and future. In the morning, I take activated charcoal (using this method) to absorb any toxins released by DIM and the cleansing of the liver.I use this DIM supplement.I take one 400 mg capsule nightly and find it to be very effective. While we understand the mechanism by which this may work and many women report benefits, it is important to note that research is lacking. In cases of microbial dysbiosis in the gut it is possible for an enzyme known as betaglucuronidase to reactivate the metabolites created in the liver and put estrogen back into circulation. My period lasts from 5-8 days and 2 of those days are very heavy and clotty where I can barely leave home soaking through super pads and tampons every 20-30 min. Physical activity: Getting regular physical activity has been proven to relieve PMS symptoms like bloating. You can get started with this free recipe guide and meal plan. During both perimenopause and menopause, hormone patterns begin to change. For example, to obtain the dosage of 100300mg of DIM recommended for women, youd need to eat a lot more broccoli and cabbage than you might want to. John Staughton is a traveling writer, editor, publisher and photographer with English and Integrative Biology degrees from the University of Illinois in Champaign-Urbana (USA). I removed many xenoestrogens and phyto estrogens from my environment hoping that would reduce my need for alot of progesterone as well as help level out my hormones. Specifically, DIM may stimulate the production of a less potent, more beneficial form of estrogen known as 2-hydroxyestrone (1). Understanding the risks. This can help prevent headaches and other unwanted issues that can arise when using a Phase 1 nutrient alone. Sorry to be graphic but I woke up and left a trail from my bed to bathroom. DIM benefits include supporting a healthy menopausal transition, promoting hormonal balance in those with polycystic ovarian syndrome (PCOS). Stay hydrated: Drinking plenty of water can help lighten your flow and reduce your chances of leakage. If you have regular periods, take five days off from the first day of your period (day 1 to 5). Researchers are looking into the anti-inflammatory and cancer-fighting effects of diindolylmethane (DIM), a compound commonly found in cruciferous vegetables including: DIM supplements appear to help adjust the hormone estrogen. Youll also benefit from the other vitamins, minerals, and fiber they provide. Supplements may be more effective. Questions about DIM. Some of their testosterone changes into estrogen and is metabolized in the liver. It contains ingredients that support Phase 1 and 2 estrogen metabolism in the liver, as well as calcium d-glucarate to ensure the body is able to safely remove estrogen from the body. Whiteley J, Dibonaventura MD, Wagner J-S, Alvir J, Shah S. The Impact of Menopausal Symptoms on Quality of Life, Productivity, and Economic Outcomes. People who take dim out of concern for its potential negative effects are likely overthinking things. My hair has been thinning for years as well as my eyebrows and much of my body hair. Drugs for Treatment and Risk Reduction: Tamoxifen. I don't break out from being on cycle (and I've run some decently heavy cycles), although I am generally not acne prone. Again, let your doctor know youre taking DIM if youre on any other medications, whether prescription or over-the-counter. In order to see the benefits, DIM should be taken daily for at least 30 days. I went on my own and started natpro. DIM alters estrogen metabolism in a beneficial way, producing more good estrogens and fewer harmful estrogens. DIM may also have an impact on your menstrual cycle. Current human research doesnt show DIM supplements to be toxic or have serious side effects. If this becomes a problem, talk to your doctor. It's easy to do. Calcium D Glucarate boosts the bodys ability to eliminate cancer-causing chemicals and estrogens. People on hormone therapies or with certain hormone-related cancers should avoid these supplements. DIM at 10mg/kg also lowered the number of . I recently ran out of the DIM and noticed my night sweats went away on day 2 of not taking them. DIM has the potential to alter your menstruation since it changes your estrogen levels. Cauley, J. For more, check out my book Hormone Repair . As a licensed naturopathic physician who is board certified in naturopathic endocrinology, she takes an integrative approach in her clinical practice. Depressedacnemess 6 mo. It also lowered estrogen levels from 8.00 pg/mL in controls to 4.56 pg/mL. "It takes . I don't need to be shelling out the extra bucks anywaylol. It will also regulate our thyroid gland, which has to do with feeling cold all the time. Typically, DIM supplements come in 50300mg capsules. That was when I added DIM to my regimen and that was when everything went haywire. avocados. DIM has shown to have a number of health benefits. I just felt like I had all the menopause symptoms and they went away when I stopped the DIM. Ugh!! Luine VN. According to studies, 30 mg of absorbable DIM per dosage is the most effective quantity of supplementary DIM, with daily doses of 60 mg for women and 120 mg for men. DIM supplements should not be taken by children or women who are pregnant or breastfeeding. Ive written at length about estrogen dominance and the impact it may have on the body. My main reason for seeking out progesterone was to help with the heavy periods I get every month. DIM is a compound your body makes from cruciferous vegetables. Estrogen imbalances have been linked to weight gain in both men and women, especially during menopause and andropause, when estrogen levels are most variable. Dim has no known harmful effects by itself, but it may cause problems when taken in high doses or if you have any kind of intestinal obstruction. So that was a plus. Oestrogen is broken down into 2 principle metabolites, 2-hydroxyestrone (2-OHE1) and 16-alpha hydroxyestrone (16alpha-OHE1). Some women who suffer from insomnia due to estrogen dominance, perimenopause, or menopause find that taking DIM at night helps them sleep better and longer. 1. Is it ok to drink alcohol while taking DIM capsules? DIM possesses hormone-modulating effects. You may think of estrogen as only a female hormone, but its not. Thanks so much Diane, for your support and input in helping me figure this out. You can take action at home by beginning to incorporate cruciferous vegetables, fiber, and other nutrients to support your hormones. We know an imbalance of estrogen and progesterone is not ideal at any time, but during the perimenopausal period, it often dramatically affects a womans quality of life. About 10% of my customers who have taken DIM have seen a difference in their menstrual cycle, Jardim adds. . It also functions as an anabolic hormone. However, these are all side effects and not risks to your health.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[300,250],'staminacomfort_com-medrectangle-3','ezslot_1',118,'0','0'])};__ez_fad_position('div-gpt-ad-staminacomfort_com-medrectangle-3-0'); Women who are using DIM as part of their birth control regimen should not use more than 5 mg of the supplement daily, and those who are pregnant or nursing should not use this amount at all. "The daily recommended intake of 600 IUs is debatable since studies show higher amounts of D are necessary for disease- and cancer-prevention benefits." Start by getting your levels checked to. If you have been following me, you might have seen the pre- and post-surgery protocol I created when facing a double hip replacement (on August 28, 2017). DIM can be taken on its own or in a combination formula with other estrogen supporting nutrients. Last medically reviewed on July 22, 2020. Scientists see lower cancer risks in people who eat a lot of vegetables. Ovasitol, for example, recommends a packet or scoop twice a day. For most women, 3-5 milligrams is a safe dose of DIM; higher doses may cause unwanted side effects. That never happens to me. The best source of DIM is fresh garlic. Our website services, content, and products are for informational purposes only. It can also help you relax after a hard day's work by reducing your anxiety levels. 4. 5 Ways DIM Benefits Estrogen Levels. It was still very heavy but I didn't leak for the first time since I could remember. In this article, we'll dive into what . If you are overweight, your body may create an excess of oestrogen, one of the hormones that govern the female reproductive system. Theyre also used to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms. Dimming out does not involve any dangerous practices so you have nothing to worry about. Some of them have shorter menstrual cycles, while others have lengthier periods, and a few have had their periods twice in one month. A: DIM is an interesting supplement and may be a bit confusing. Being overweight might also have an impact on your menstrual period. Losing weight can help improve your menstrual pattern. Read Guide to using progesterone for women's health. Its important to support the entire system of estrogen metabolism. When the endometrial lining is overstimulated it can result in endometrial hyperplasia, which can lead to heavier periods. . Periods that are irregular. Learn more about Balance Womens Hormone Support. In vitro and in animal studies suggest DIM has anti-inflammatory , antiproliferative . It's great that it works for you and your daughter. Always talk to your doctor before adding a supplement to your diet., Denver Vein Center: DIM Supplements: What You Need to Know., Harvard Health: By the way, doctor: What does Indolplex do? Getting your vitamins and minerals through diet., Memorial Sloan Kettering Cancer Center: Diindolylmethane., Toxicology Letters: Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.. I can see some light at the end of the tunnel!!! The recommended dosage of myo-inositol for most women with PCOS is 4000 mg/day taken in two doses. While estrogen levels decrease during menopause, the truth is, estrogen levels do not fall significantly until after a woman's last period. Taking DIM without food may cause digestive problems, nausea, and vomiting. Incidentally, using pads for urinary incontinence has helped a little. DIM has been discovered to protect normal cells. Memorial Sloan Kettering Cancer Center. I upped my NAC and CDG and Natpro to about 200 mgs. When you eat cruciferous vegetables, your stomach acid breaks down a compound called indole-3-carbinol to produce a new compound called DIM (3). Brighten, J.. Natural Remedies for Cramps & PMS. The week before it began I had some cramping and spotting. DIM is a compound your body creates when you eat cruciferous vegetables. Find out about natural and pharmaceutical, Chemicals may seem like the best route for acne-prone skin, but its not your only option. Perimenopause is the period between a womans later reproductive years and menopause. Another way to reduce estrogen is to take a phytonutrient derived from broccoli called DIM (diindolylmethane) (10). I know the dosage is low compared to what is advised on this site. You should only use natural remedies during your period if they are intended for feminine hygiene purposes only. You are encouragedto refer any health problem to a health care practitioner and, in reference to any information contained in thisweb site, preferably one with specific knowledge of, Join in and write your own page! If youre of reproductive age, estrogen is necessary to support healthy breast, bone, and endometrial tissue. Am I not supposed to take it after ovulation? Then it began heavy with clotting, but not as bad as it usually is. The average duration is three to four years, although it can last just a few months or extend as long as a decade. After all, vegetables like broccoli and kale are rich sources of important nutrients, including fiber, antioxidants, vitamins, and minerals. DIM may be effective at inhibiting aromatase. The most favorable of the three is 2OHE1. This increased burden can lead to problems such as diabetes and high blood pressure, both of which may also influence your period cycle. Progesterone also stabilizes the HPA (adrenal) axis and supports thyroid function. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. I didn't see much of a difference until I learned to up the dose and stop taking during my period. But I think if you take DIM all days it can also increase your testosterone levels. What is the recommended dosage of DIM? "It binds to the androgen receptor so that there's no 'hole' for the androgen 'keys' to bind to," says Dr . Boy was I wrong! DIM stimulates the body to . People also ask, When should I take DIM morning or night? Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice thatis not captive to purely commercial interests, or blinded by academic and institutional hubris. It may also help reduce the effects of a stronger form called 16 alpha-hydroxyestrone, which has been linked to weight gain and an increased risk of some cancers, including breast and uterine cancer (1, 7). If we have estrogen dominance, it will work out which hormone is less and get the body to create more of the hormone we need. Remember that it requires you to chew well and have healthy hydrochloric acid levels present in the stomach. While the exact mechanism is unknown, indole-3-carbinol is thought to be partly responsible (4, 5, 6). It was very unusual. Still, more human research is necessary (15). Calcium D-glucarate inhibits beta-glucuronidase, see. This is why you must take the dosage of the supplement into account. Estrogen dominance could unfortunately come about for various reasons: anovulation (no ovulation), stress, adrenal issues, excess fat in the body, the environment, digestive problems, and autoimmune conditions. reducing . (not sure the exact amount because I eyeball it). It can be difficult to meet the increase in iron through . People who use the DIM supplement as part of a weight-loss regimen might expect to see effects in six weeks to six months. As for the second question, the answer is yes, you can try diming out for yourself. The rest of the period is normal with surprise flooding now and then even on the last day. Diindolylmethane (DIM) is a compound created when you digest cruciferous vegetables, such as broccoli or Brussels sprouts (1, 2). What are some alternatives to diming out? There is also data to support its benefits in certain cancers. In fact, it may help combat prostatic intraepithelial neoplasia (PIN), a condition thats characterized by prostate cell growth and considered to be a precursor to prostate cancer (14). It breaks the glucoronide bond between a toxin and glucuronic acid, and releases carcinogens, toxins and excess steroid hormones back into circulation. If youve been struggling with PMS symptoms, heavy periods, acne, breast tenderness or symptoms of PCOS or perimenopause then youve probably come across a DIM supplement as a solution. For fertility: begin taking the herb regularly (daily) three months before you'd like to conceive. When broccoli, cauliflower, and other cruciferous vegetables are exposed to stomach acid after chewing, indole-3-carbinol is created, which is then converted into DIM. Slows some cancer cells. What to Eat During Your Period - Keep It Warm and Balanced. Finally, dim light has been known to make sleep problems worse for people who struggle with insomnia. Left unchallenged, estrogen is allowed to stimulate tissues and as it goes through its own peaks and troughs, it can trigger hot flashes, night sweats, and mood swings. This is why drinking ample water, eating fiber, supporting microbiome health, and ensuring regular bowel movements is so important to your hormone health. I had cramps everyday. Place a heating pad or hot water bottle over the plastic-covered flannel. Thus, you should talk to your healthcare provider before taking DIM supplements. Some women who suffer from insomnia due to estrogen dominance, perimenopause, or menopause find that taking DIM at night helps them sleep better and longer. The Benefits of DIM. Before using DIM, anyone with liver or renal illness should talk to their doctor. During Phase 1 your liver converts estrogen into 3 metabolites2 hydroxy estrone (2OHE1), 4 hydroxy estrone (4OHE1), and 16 hydroxy estrone (16OHE1). After a year without a period a woman is considered to be in menopause. The eggs are super tiny too small to see with the naked eye. So the goal would not be to drop estrogen as low as possible. Estrogen dominance symptoms might mimic those of perimenopause, menopause, or even PMS. Certain medical issues might also have an impact on your menstruation. Inactivity. Your menstrual cycle and period are controlled by hormones like estrogen and progesterone. A plant based whole unprocessed food diet is recommended to help shrink fibroids. When using DIM supplements, some persons have reported mild changes in urine color. First, I suggest avoiding the foods below for just 2-4 weeks to see if there is improvement in symptoms. DIM may interfere with the way your liver breaks down some drugs. Calcium D-glucarate is a supplemental form of glucaric acid, an important naturally occurring chemical that helps remove toxins and unneeded hormones from the body. Before using DIM, those who are at a greater risk for estrogen-sensitive malignancies other hormone-related diseases should talk to their doctor. Estrogen levels may be determined in the blood, urine, or saliva. This work is licensed under a Creative Commons Attribution 3.0 Unported License, Hello. So if you take DIM during your period time and start BO with Vitex it helps a lot. The night sweats come about 11 days before my period and can run into when I have my period. Estrogen Dominance: 15 Signs Mood changes. For instance, some studies suggest DIM encourages the death of cancer cells. Secondly, Should DIM be taken with or without food? DIMis a compound that can only be made from cruciferous vegetables. Made from non-GMO-certified soybeans, this product is a plant-based source of phytoestrogens to provide holistic supplementation for a . Sex Drive has decreased. Taking Iron During Your Period. After reading reviews from people, there were a couple that were post menopausal but started having periods again due to the hormonal changes from taking the DIM. Because DIM metabolites have an amber tint that bleeds into your urine, this occurs. Although there is research and anecdotal evidence to suggest benefits, it is important to note that more data is needed. DIM may help your body maintain healthy testosterone levels. As Ive already mentioned, DIM promotes the production of more beneficial estrogen metabolites (2OHE1), and discourages the production of problematic estrogen metabolites (such as 16OHE1). However, DIM supplements are available over-the-counter and online. I have missed a day here and there. Supplements can help. And they're linked to high estrogen (and low progesterone). Problems can arise when there is too much estrogen circulating in our bodies or the wrong metabolites. I took it as a sign that the DIM was working. Research suggests that DIM affects estrogen levels in your body (1). I was so bloated. Studies have shown that women in perimenopause and menopause experience a reduced health-related quality of life, as well as higher work impairment. As Ill explain in this article, DIM supports the body in producing more favorable estrogen metabolites, specifically 2-hydroxy estrogen (2OH). The same thing goes for individuals who are allergic to garlic or have high blood pressure, heart disease, or diabetes. While DIM is often used to support hormone balance in premenopausal women, it also may cause hormonal disturbances. By Stephanie Garr (Certified Nutrition Consultant) DIM is a particular supplement that has been growing in popularity, especially among women, because it can help correct hormonal imbalances. Simply click here to return to Progesterone faq. Promotes healthy estrogen metabolism - DIM helps the body break down "bad" estrogen to be properly eliminated allowing for "good" estrogen to do its job and participate in healthy hormonal balance. My period is 2 days late, and it never is normally late. Have been stable on Synthroid until Menopause. This web site offers health, wellness, fitness and nutritional information and is provided for informational purposes only. I will keep you apprised with an update. Bleeding generally occurs only four times a year during the seven days you take the inactive pills. Don'ts Exercise on a regular basis. What does the thyroid have to do with estrogen? Researchers concluded that, in women taking tamoxifen, DIM promoted healthier estrogen metabolite production. The results will depend on your body, your diet, and your hormones. Another study shows that increased levels of 16OHE1 may lead to a greater chance of thyroid proliferative disease. Estrogen imbalance or excess estrogen, often called estrogen dominance can lead to a cascade of undesirable symptoms like hormonal headaches, breast tenderness, and PMS, to name a few. I started to have extreme night sweats to the point I couldnt sleep because it was like I jumped into a pool. These risks will be discussed in more detail below. If you are struggling with heavy periods, tender breasts, mood swings, hot flashes and water retention, there is a high chance that you are estrogen dominant. I've been taking 200mg of DIM once a day for 6 months and . The majority of individuals find that taking DIM first thing in the morning with a glass of water and a little amount of food is the best way to proceed. And supplementation may sometimes be a useful tool in helping the body optimize your hormones. Avoid high glycemic foods such as refined sugar. A.. Estrogen and Bone Health in Men and Women. The only hormone metabolites known to help with appropriate levels of the free form of testosterone are the 2-hydroxy metabolites of estrogen induced by DIM. While a DIM supplement may be helpful for some women, it is not essential for everyone. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Video: Why You Need Zinc and Where to Find It. September 1, 2019 at 8:39 am. Research shows that about one in three cancer deaths is related to poor nutrition and could be prevented. "I would say about 10% of my clients who have used DIM see a change in their menstrual . This transitional period before menopause is known as perimenopause, and it can begin long before you enter menopause. I feel like it was removing my estrogen to the point it was putting me into menopause. In polycystic ovarian syndrome, this is often beneficial (PCOS). They were also significantly lighter. A fierce patient advocate and completely dedicated to uncovering the root cause of hormonal imbalances, Dr. Brighten empowers women worldwide to take control of their health and their hormones. DIM Promotes Fat Decomposition DIM is linked to estrogen metabolism, which is important for body weight regulation.

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