This information is not individual medical advice and does not substitute for the advice of your health care professional. Applies only to oral form of both agents. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Applies only to oral form of both agents. Iron sucrose: 20 mg/mL. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Pregnancy: Risk Summary-Clinical Considerations. Since this is less than the threshold of total dose of 20 mg/kg, the deficit can be eliminated with a single infusion. Maximum single dose of iron sucrose to be given at a time in Non-dialysis CKD patients is 500 mg but with limited experience. Human studies not conducted. Administer Injectafer intravenously, either as an undiluted slow intravenous push or by infusion. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Applies only to oral form of both agents. Administer on 5 different occasions over a 14 day period. Estimates the iron deficit in preparation for iron replacement based on patient weight and haemoglobin. Each mL contains 20 mg of elemental iron. Manage and view all your plans together even plans in different states. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. The dosing for iron replacement treatment in pediatric patients with Peritoneal or Hemodialysis-Dependent - CKD or Non-Dialysis Dependent CKD have not been established. Avoid or Use Alternate Drug. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. Venofer is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). This iron deficiency calculator determines the iron deficit based on patient weight, hemoglobin and iron stores to prepare for iron replacement. The above information is provided for general Use Caution/Monitor. Separate dosing of tetracyclines from these products. Use Caution/Monitor. Venofer is given as an infusion into a vein. This document does not contain all possible drug interactions. Excessive therapy with parenteral iron can lead to excess storage of iron with the possibility of iatrogenic hemosiderosis. Prior to and at regular intervals during parenteral iron therapy, evaluate serum iron, hemoglobin, and hematocrit. Monitor Closely (1)vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Iron deficit - equation derivation: Assumptions: -Blood volume = 65 mL/kg -Hemoglobin conc target =14.0 g/dL -Deficits in body stores are ignored. Hollands J, Foote E, Rodriguez A. Applies only to oral form of both agents. iron sucrose increases levels of calcium citrate by enhancing GI absorption. 1970; 100(7):301-3. Use Caution/Monitor. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Drug Des Devel Ther; 5: 5160. IDA diagnosis is based on full blood examination and on the serum ferritin level. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Mode of Administration: Administer Venofer only intravenously by slow injection or by infusion. Available for Android and iOS devices. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Ferritin and transferrin are also recommended monitoring . DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. Venofer treatment may be repeated if necessary. Indications: Feraheme is indicated for the treatment of iron deficiency anemia (IDA) in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron or who have chronic kidney disease (CKD). Use Caution/Monitor. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Oral iron therapy is the first method while IV therapy comes in place when there are contraindications or the body doesnt respond to the oral one. Separate dosing of tetracyclines from these products. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Last updated on Jun 1, 2022. Nutrition. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Ferrlecit may be diluted in 100 mL of 0.9% sodium chloride administered by intravenous infusion over 1 hour per dialysis session. Use Caution/Monitor.Minor (2)calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf. nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. gymnema decreases levels of iron sucrose by inhibition of GI absorption. Slowing the infusion rate may alleviate symptoms. Ganzoni AM. Applies only to oral form of both agents. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . Treatment of anemia due to iron deficiency. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. May increase risk of hypotension. Included in the iron dextran package insert. It should be recognized that iron storage may lag behind the appearance of normal blood morphology. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. Avoid or Use Alternate Drug. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 commonly, these are "non-preferred" brand drugs. Applies only to oral form of both agents. 1998 Feb;25(1):65-8. 1. Applies only to oral form of both agents. Use Caution/Monitor. Kumpf VJ, Holland EG. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. All Rights Reserved. Separate dosing of tetracyclines from these products. Applies only to oral form of both agents. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] -Volume of parenteral iron product req'd (mL) = [Iron deficit (mg)] / C(mg/mL) Final calculations: -Hgb iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) -Volume of product required (mL) = [weight (kg)x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Avoid or Use Alternate Drug. Administer a test INFeD dose prior to the first therapeutic dose. Avoid or Use Alternate Drug. Immune system disorders: Anaphylactic-type reactions, angioedema, Nervous system disorders: Convulsions, collapse, light-headedness, loss-of-consciousness, Respiratory, thoracic and mediastinal disorders: Bronchospasm, dyspnea, Musculoskeletal and connective tissue disorders: Back pain, swelling of the joints, General disorders and administration site conditions: Hyperhidrosis, Published studies on intravenous iron sucrose treatment after first trimester of pregnancy not shown adverse maternal or fetal outcomes; available reports of intravenous iron sucrose use in pregnant women during first trimester are insufficient to assess risk of major birth defects and miscarriage; iron deficiency anemia during pregnancy should be treated because there are risks to mother and fetus associated with untreated iron deficiency anemia (IDA) in pregnancy; risks to fetus associated with maternal severe hypersensitivity reactions, Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products which may cause fetal bradycardia, especially during second and third trimester, Iron sucrose is present in human milk, and available published reports following exposure to 100-300 mg intravenous iron sucrose have not reported adverse reactions in breastfed infants; there are no data on effects on milk production, Developmental and health benefits of breastfeeding should be considered, along with mothers clinical need for treatment and any potential adverse effects on breastfed child from therapy or from underlying maternal condition. Crown Rump Length and Nuchal Translucency. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Applies only to oral form of both agents. Assessing new treatment options. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. Applies only to oral form of both agents. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. Use Caution/Monitor. * Calculators are available in UpToDate to determine ideal body weight and lean body weight. Dosing Considerations (8-10) Maximum single dose of iron sucrose in all other patients is 300 mg every week. Fatal reactions have also occurred in situations where the test dose was tolerated. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Applies only to oral form of both agents. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. View the formulary and any restrictions for each plan. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Applies only to oral form of both agents. Where C is the concentration of the iron product: Please note that the calculations above are for information purposes only and the individual dose needs to be established by taking into account the current package insert for the elemental iron product used. Schrier SL, Mentzer WC, Landaw SA. Applies only to oral form of both agents. ------------------------------------------------------------------------- Iron Dextran Complex [ Infed ] Elemental iron: 50 mg of elemental iron per mL [2 mL] [package insert] BOXED WARNING: WARNING: RISK FOR ANAPHYLACTIC-TYPE REACTIONS Anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. Normal haemoglobin values are gender specific: for males from 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17mmol/L) and females from 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37mmol/L). Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . UpToDate. When administering as a slow intravenous push, give at the rate of approximately 100 mg (2 mL) per minute. Med J Aust; 193(9):525-32. This site contains information for licensed healthcare professionals in the United States. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Use Caution/Monitor. DICP. All Rights Reserved. A target haemoglobin value is also input so iron deficit can be determined according to a specified individual target. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Minor/Significance Unknown. Monitor Closely (1)sodium sulfate/potassium sulfate/magnesium sulfate decreases levels of iron sucrose by inhibition of GI absorption. Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Adult Dosage and Administration: The recommended dosage of Ferrlecit for the repletion treatment of iron deficiency in hemodialysis patients is 10 mL of Ferrlecit (125 mg of elemental iron). Applies only to oral form of both agents. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Minor/Significance Unknown.iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Use Caution/Monitor. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. Applies only to oral form of both agents. Applies only to oral form of both agents. iron sucrose decreases levels of moxifloxacin by inhibition of GI absorption. For liquid medications, also enter the value of the Medicine Concentration and choose . sodium sulfate/potassium sulfate/magnesium sulfate decreases levels of iron sucrose by inhibition of GI absorption. IMPORTANT SAFETY INFORMATION DOSAGE AND ADMINISTRATION Pediatric Patients (2 Years of Age and Older) Use Caution/Monitor. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Ensure the Intravenous Iron Checklist (see trust guideline) has been completed. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. This drug is available at a higher level co-pay. Interaction only with oral iron administration. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Formula for calculating the required dose of iron sucrose 1. Deferasirox chelates iron. Applies only to oral form of both agents. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Share cases and questions with Physicians on Medscape consult. The dosage of Venofer is expressed in mg of elemental iron. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Applies only to oral form of both agents. Venofer may reduce the absorption of concomitantly administered oral iron preparations. Separate dosing of tetracyclines from these products. iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Serious - Use Alternative (1)iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Either increases effects of the other by pharmacodynamic synergism. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Applies only to oral form of both agents. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Nutr Clin Pract. Accessed: 4/12/2011. This health tool computes the required parenteral iron replacement dose for the iron deficit extracted from the patient weight and hemoglobin level from complete blood count test. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Your doctor will do laboratory tests to monitor your response. iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. commonly, these are "preferred" (on formulary) brand drugs. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. By using this form you agree with the storage and handling of your data by this website. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. Properly discard this product when it is expired or no longer needed. For patients weighing less than 50 kg (110 lb): Give Injectafer in two doses separated by at least 7 days. Then enter the value of the Dosage and choose the unit of measurement from the drop-down menu. Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Iron Sucrose [ Venofer ] Elemental iron: 20 mg/mL (2.5 mL, 5 mL, 10 mL) Solution, Intravenous [preservative free]: [package insert] INDICATIONS: Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD). The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. Calculates iron deficit for dosing iron. Applies only to oral form of both agents. Iron deficiency anemia is the type of anemia caused by iron depletion. Written by ASHP. Deferoxamine chelates iron. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. iron sucrose decreases levels of deferiprone by enhancing GI absorption. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Either decreases levels of the other by inhibition of GI absorption. Minor/Significance Unknown. dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. Maximum infusion rate: 100 mg / hour (Slow infusion rate of iron sucrose is recommended to minimize adverse reactions, especially hypotension) Frequency of infusion: Dose may be repeated up to 3 times weekly to provide total iron dose. Minor/Significance Unknown. Applies only to oral form of both agents. This product may contain inactive ingredients, which can cause allergic reactions or other problems. iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Avoid or Use Alternate Drug. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. restrictions. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Applies only to oral form of both agents. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. Avoid or Use Alternate Drug. however iron sucrose requires multiple small intermittent doses over days to weeks. No data are available regarding overdosage of Venofer in humans. During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. Use Caution/Monitor. By clicking send, you acknowledge that you have permission to email the recipient with this information. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. Minor/Significance Unknown. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Last updated 28/06/2018 Enter values here and press 'Calculate'. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] Intravenous iron sucrose: establishing a safe dose. Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. Fill in the calculator/tool with your values and/or your answer choices and press Calculate. Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes. PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Use Caution/Monitor. Treatment of anemia due to iron deficiency. Applies only to oral form of both agents. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Iron supplements, whether administered orally, intramuscular or intravenous, are used to replenish body stores and correct anemia. feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Monitor Closely (1)calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Methods. ------------------------------------------------------------------------- Ferric Carboxymaltose [ Injectafer ] Elemental iron: Injectafer contains 50 mg of elemental iron - 750 mg/15 mL [package insert] Indications: Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron; who have non-dialysis dependent chronic kidney disease. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. A maximum dose of 1000 mg iron can be delivered intravenously over 15 minutes, which may make it a suitable treatment for iron-deficiency anaemia outside of the hospital setting. Venofer [package insert]. Medicinal forms Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Applies only to oral form of both agents. There is in depth information below the form on the method used and on the result provided. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Separate by at least 4 hours. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. J Med. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW Applies only to oral form of both agents. Applies only to oral form of both agents. Human studies not conducted. Applies only to oral form of both agents. Applies only to oral form of both agents. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. Monitor Closely (1)pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. We'll do this entirely for free, as long as the calculator has applications for women's health.

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